According to the NRC, what is the maximum allowable 99Mo concentration in 99mTc eluate at the time of administration to the patient?

The maximum allowable concentration of 99Mo in 99mTc eluate at the time of administration is established by regulations to ensure patient safety and minimize radiation exposure. The limit of 0.15 microcuries (uCi) of 99Mo per millicurie (mCi) of 99mTc is a well-defined standard set by the Nuclear Regulatory Commission (NRC).

This limit is crucial because 99Mo is a parent isotope that decays to 99mTc, and the presence of 99Mo can contribute to unnecessary radiation exposure to the patient. Maintaining this concentration limit ensures that the amount of 99Mo is kept to a level that is considered acceptable according to safety guidelines and helps in the effective use of the diagnostic properties of 99mTc while ensuring patient health is not compromised.

In clinical practice, adherence to this guideline helps nuclear medicine professionals avoid potential harmful effects associated with higher levels of radioactive materials during diagnostic procedures.