Thyroid imaging may be performed with which of the following radiopharmaceuticals?

Thyroid imaging is primarily performed using 99mTc pertechnetate because this radiopharmaceutical is specifically taken up by the thyroid gland, similar to how iodine is absorbed. 99mTc pertechnetate mimics iodide uptake, allowing for the assessment of thyroid function and morphology. The radiopharmaceutical is used to visualize the gland and identify lesions, nodules, or any abnormal uptake patterns in the thyroid.

In contrast, the other options serve different purposes in nuclear medicine. 99mTc sestamibi is typically used for imaging myocardial perfusion and detecting parathyroid adenomas, while 99mTc medronate is used for bone scanning to assess skeletal conditions. 99mTc sulfur colloid is employed for liver and spleen imaging and is not involved in thyroid imaging. As such, 99mTc pertechnetate is the appropriate choice for visualizing the thyroid gland based on its preferential uptake and utility in this specific application.