Which administration technique is recommended for 99mTc bicisate?

The recommended administration technique for 99mTc bicisate is an infusion over 3 hours due to the need for a controlled and steady delivery of the radiopharmaceutical. This method allows for a gradual accumulation of the tracer in tissues, ensuring that there is adequate time for the agent to reach its target and for optimal imaging results.

A direct venous stick might lead to a more rapid delivery that does not allow for the planned pharmacokinetics of the agent, potentially affecting the imaging quality. Bolus injection could also result in a rapid rise and subsequent decline of the tracer concentration, which may not be suited for the required imaging protocols. Infusing at peak cardiac could introduce variability in the timing and concentration of the radiopharmaceutical, which can compromise the quality of the imaging results.

Thus, the infusion over 3 hours is the preferred method because it ensures the stability and reproducibility necessary for effective imaging and assessment of myocardial perfusion, which is the primary application of 99mTc bicisate in nuclear medicine.