Which radiopharmaceutical should be prepared for a renal function study to determine the glomerular filtration rate?

For a renal function study aimed at determining the glomerular filtration rate (GFR), the appropriate radiopharmaceutical is 99mTc pentetate. This radiopharmaceutical is specifically designed for renal imaging and is a classic agent used for assessing renal function due to its ability to be filtered by the glomeruli.

99mTc pentetate is a technetium-labeled diethylenetriaminepentaacetic acid (DTPA) derivative, which closely mimics the behavior of creatinine in the body. It gets cleared from the bloodstream by the kidneys, and the rate at which this radioisotope is excreted allows for an accurate calculation of the GFR. The measurements obtained using 99mTc pentetate are reliable indicators of renal function and help in identifying potential dysfunction.

The other options, while they may have various clinical purposes, do not serve as suitable agents for GFR determination. For example, 99mTc gluceptate and 99mTc mertiatide (also known as 99mTc MAG3) are used in renal imaging but are not the gold standard specifically for measuring GFR. 99mTc sulfur colloid is primarily used for different imaging purposes